During replication and transmission of HIV (green), RNA is converted to DNA. With the CDC urging screening for all willing patients, providers will be testing and managing a growing number of ...

HIV-1 protease inhibitors (PIs) have long been central to antiretroviral therapy, directly targeting the enzyme responsible for processing viral polyproteins into functional units. Their efficacy, ...

HIV is a lifelong infection that, without proper antiviral treatment, will kill cells of the immune system and leave individuals susceptible to infections and cancers. The longevity of this virus ...

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human ...

A groundbreaking discovery reveals how HIV integrates its genetic material into human DNA, exposing a key viral vulnerability that could lead to new therapies and bring the world closer to a ...

Since HIV’s discovery in the 1980s, scientists have come a long way in understanding the different steps required for its assembly and maturation. Researchers knew, for instance, that HIV wraps its ...

HIV scientists have long sought to unravel the mysteries of viral latency – a stealthy tactic the virus employs to evade the body's immune defenses. Recent research from the University of North ...

Sunlenca (lenacapavir) is a medicine that was approved by the FDA in 2022 to treat HIV in combination with other HIV medicines. Sunlenca has a unique mechanism of action and is the first medicine in ...

Two thirds of HIV care providers surveyed screen for nonalcoholic fatty liver disease (NAFLD) in patients with HIV (PWH). The main barriers to fatty liver screening are uncertainty about tests, ...