How CRISPR Works: Unpacking the Science of Cas9 and Gene Modification

Discover how CRISPR genome editing is revolutionizing medicine. Learn the science of Cas9, current clinical trials, and the ...
Medical Xpress

CRISPR gene editing in blood stem cells linked to premature aging effects: Study offers solutions

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and ...
Nanowerk

Silicon nanotube arrays deliver mRNA into human stem cells while preserving pluripotency

Silicon nanotube arrays deliver functional mRNA into human pluripotent stem cells for the first time, achieving up to 64% transfection without compromising stem cell identity.
News Medical

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and ...
GEN

Epigenetic Editing of Mouse Stem Cells Generates Embryoids for Developmental Research

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...
UC San Francisco

Novel Gene Therapy Trial for Sickle Cell Disease Launches

UCSF Benioff Children’s Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 ...