Celiac disease is common and can present with nonspecific upper gastrointestinal symptoms. Patients may therefore undergo esophagogastroduodenoscopy as their initial investigation. Markers of villous ...

A research team from Spain evaluated the predictive value of tissue transglutaminase (tTG) antibodies for villous atrophy in adult and pediatric populations to determine if duodenal biopsy can be ...

Despite advances in our knowledge of celiac disease, the most current and authoritative recommendations conclude that diagnosis requires at least four biopsy specimens to be taken from the duodenal ...

Adults with suspected celiac disease and no immunoglobulin A (IgA) deficiency most likely can avoid a diagnostic bowel biopsy if they have high serum anti-tissue transglutaminase IgA (tTG-IgA).

Please provide your email address to receive an email when new articles are posted on . Age at diagnosis, disease pattern, clinical response and gluten-free diet adherence predicted risk for ...

Endoscopic images of the descending duodenum showed a granular mucosa with scalloped folds; spraying with 0.2% indigo carmine solution revealed a mosaic pattern and the absence of villi. Results of ...

Villous atrophy occurs when your intestinal villi—the microscopic, finger-like tentacles that line the wall of your small intestine—erode away, leaving a virtually flat surface. Celiac disease, an ...

Please provide your email address to receive an email when new articles are posted on . The positive predictive value of serum anti-tissue transglutaminase IgA was 93.9%. Serum levels of 10 times the ...

A blood test may be reliable in diagnosing some adults with suspected celiac disease, helping to avoid a biopsy, according to a prospective cohort study. In 436 adults with suspected disease and ...

Duodenal biopsy remains the gold standard for celiac disease (CD) diagnosis. However, it has several pitfalls and requires an invasive procedure in children. In the past few years, a more prominent ...