To understand the pharmacology and mechanism of action of ximelagatran, a review of the formation and function of thrombin is warranted. [10] The generation of thrombin is limited under normal ...
OPTIMAL conversion of prothrombin to thrombin requires the presence of at least four factors, namely, factor V (pro-accelerin, Ac-globulin), factor X (Stuart-Prower factor) in an activated form (Xa), ...
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