The wide adoption of genetic engineering techniques in the late 1990’s played an important role in demonstrating the complexity and importance of communication between stromal cells and immune cells ...
A flow cytometry-based approach to isolate extracellular vesicles is evaluated and its impact on microRNA cargo is revealed, showing reduced molecular diversity while preserving core functional ...
Gastrointestinal stromal tumours (GISTs) are rare stomach tumours driven by KIT or PDGFRA gene mutations. Unlike typical gastric cancers, they respond well to targeted therapy such as imatinib. Early ...
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The 3 types of ovarian cancer and how they are different
Medically reviewed by Renita White, MD Key Takeaways Epithelial ovarian carcinoma is the most common type of ovarian cancer.Germ cell tumors often affect teenagers and young adults.Stromal tumors are ...
Multimodality Therapy for Locally Advanced Cervical Carcinoma: State of the Art and Future Directions We reviewed the current evidence on the clinical management of these relatively rare ovarian ...
Dr. Rosario Ligresti explained that while many GISTs are found incidentally, larger tumors may cause anemia, bleeding or swallowing issues. Anemia and gastrointestinal bleeding are among the most ...
The Lupus Foundation of America (LFA) is excited to share that enrollment for the MiSLE (Mesenchymal Stromal Cells in Systemic Lupus Erythematosus) study was officially completed on February 21, 2025 ...
To study the pharmacokinetics (PK) of imatinib (IM) in patients with advanced GI stromal tumors (GISTs) treated in a randomized phase II study and to explore the potential relationship between IM ...
We used STI571 (Glivec, Novartis, Basel, Switzerland), 7 an inhibitor of the tyrosine kinase activity of c-kit, in a patient with a gastrointestinal stromal tumor. In October 1996, a 50-year-old, ...
Reviewed by Michael Greenwood, M.Sc. Stroma is the region of an organ or tissue that has a connective or structural role and is also comprised of all of the constituents that do not have a specific ...
Medical emergencies don’t usually come with much warning. One moment everything feels manageable, and the next, the body starts giving serious signals.
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