The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these ...

A picture of a mouse MII stage eggs with the location of chromosomes (green) and the distribution of the histone modification H3K4me3 (purple). The team confirmed that H3K4me3 was significantly ...

How do immature egg cells maintain genetic quality for decades before they mature? Scientists find unusual safeguards in this quiescent cell that may inform research into fertility. Out of all the ...

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...