A key aspect of Parkinson’s disease (PD) pathophysiology is decreased systemic regulatory T cell (Treg) function with associated neuroinflammation in the nigrostriatal pathway of the brain, including ...
(A) In early/mid-stage PD, the nigrostriatal pathway (indicated by red arrow) is primarily affected, leading to impaired voluntary movement control due to dopamine depletion in the striatum. During ...
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