A decline in the expression of the epigenetic regulator Setd8 in neural stem cells (NSCs) during early adulthood leads to chromatin condensation and reduced gene expression, suppressing NSC ...

Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators have defined a ...

Researchers have defined a new genetic disease caused by a mutation in the IVNS1ABP gene. The condition marks a rare ...

Age often brings a gradual decline in the ability to learn new things and retain memories. This phenomenon, often associated with the elderly, is linked to the brain's deteriorating capacity to ...

A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators have defined a new genetic disease marked by premature aging and deficits in brain function.

For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis – the birth of new neurons – is now a widely ...

A single-cell atlas of brain aging epigenetics has mapped methylation, chromatin, and gene activity changes across 36 cell ...

Scientists are no longer just cataloging the damage that comes with age, they are starting to rewire the machinery inside cells that makes that damage accumulate in the first place. A new wave of work ...

SAN CARLOS, Calif.--(BUSINESS WIRE)--Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning to target aging, in collaboration with researchers at the ...