Mouse embryonic stem cells (ESCs) have emerged as ideal tools for developmental biology research due to their characteristics such as unlimited proliferation and pluripotent differentiation potential.
Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...
Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...
Neural crest cells are a population of stem cells that invade the embryo in early development. They play a big role in what ...
Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...
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Researchers discover L1td1 maintains stem cell pluripotency by degrading totipotency-associated RNAs
A new study has found that L1td1, a protein evolutionarily co-opted from the Long interspersed nuclear element 1 (LINE1) ...
Researchers have developed a method to confidently produce blood cell precursors from stem cells in mice, by activating a set of seven key genes in the laboratory. The team takes a step forward ...
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