During high volumes of drug screening, different types of assays have been shown to be useful for detection. But, toward the end of these drug screenings, the positive hits have to be confirmed in ...

The poster also demonstrates endogenous receptor activity in CHO-K1 and HEK-293 cell lines stably expressing the GloSensor plasmid. In addition, transfected Gs- and Gi-coupled receptor activity are ...

G-protein-coupled receptors (GPCRs) participate in a broad range of physiological functions. A priority for fundamental and clinical research, therefore, is to decipher the function of over 140 ...

Protein-protein interactions are at the heart of all cellular processes. To understand how cells work, and to develop effective interventions when cellular processes go awry, researchers need ...

The last two decades have witnessed the steady growth of the protein drug market. As original recombinant products come off patent, generics/ biosimilars are also beginning to be manufactured. The ...

Understanding the kinetics of protein folding that are linked to protein stability is essential to gain knowledge about the structure, energetic and dynamic properties of proteins. Carrying out ...