Microscopy image of a PGA at day 8 showing the early tissues supporting the embryo, including the amniotic sac and the yolk sac-like structures, surrounded by (extra-embryonic) mesoderm tissue.

Collaborative work has developed a cell culture system that differentiates human pluripotent stem cells to amniotic ectoderm and surface ectoderm based on cell density. Research conducted by Dr Shota ...

Researchers have succeeded in generating high-quality feline embryonic stem cells using sperm and eggs from testes and ovaries discarded during sterilization surgery. As different as they may seem, ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...

Figure 1: A fluorescence image of an induced presomitic mesoderm (iPSM) tissue model, where cells expressing the Hes7 gene—a key regulator of somite formation—are labeled green. Purple cells express a ...

Embryonic germ layers are the fundamental organizing principle in animal development. They provide the structural basis from which tissues and organs arise. During early embryogenesis, cells divide to ...

Receptor tyrosine kinases (RTKs) are a large group of integral membrane signaling molecules. Mutations in the RTK anaplastic lymphoma kinase (Alk) protein have been linked with non-Hodgkin lymphoma, ...

A cell aggregation of human pluripotent stem cells and amniotic ectoderm cells generated by the published culture method and mimicking the gastrulation event in human embryos. Gray: nuclei, Cyan: ...