An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...
Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...
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Dancing proteins keep cells moving: Redefining the function and role of key factors in actin filament disassembly
Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to be closed or chase down bacteria in the bloodstream. This mobility is ...
“We are answering fundamental questions of life that scientists have been trying to answer for several decades”, remarks Raunser. In eukaryotic cells, actin proteins are abundant and tend to join ...
Cells in the human body are made to move. They assemble during embryo development, migrate to repair tissue, hunt pathogens, and perform a host of other tasks requiring travel. As part of the ...
Research has demonstrated that actin waves propagate via actin polymerization on the substrate-attached cell membrane at the wave’s front and disassembly at the back of the wave. 4 Proteins named Arp2 ...
Living cells are highly organized, yet they are not assembled using rigid blueprints or by following a predetermined plan. Instead, order emerges on its own from countless interactions between ...
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