Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...

Deep-learning model decodes the regulatory effects of DNA changes ...

What makes every person unique? Part of the answer is in our genes. A gene is a basic unit of heredity, the means by which traits get passed from one generation to the next, and genetics is the study ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...

Once disregarded as “junk DNA,” scientists now know that this molecular dark matter is crucial for determining gene activity in ways that keep us healthy—or cause disease. Exactly how this DNA shapes ...

A new gene editing technique derived from bacterial “jumping genes” can add, remove, recombine and invert DNA sequences, potentially overcoming some of the limitations of CRISPR. The approach is made ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can ...