Two new tools created at Gladstone Institutes allow scientists to study DNA at single-molecule resolution using fewer cells than previously required, with clear applications for cancer and many other ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...

Drawing inspiration from natural cell signaling cascades, chemists at Université de Montréal (UdeM) have developed a DNA-based signaling cascade that allows them to quantify and report via an easily ...

Atomic Force Microscopy-based SMFS is widely used due to its high force sensitivity and spatial resolution. In this technique, a biomolecule is attached between a surface and an AFM cantilever. As the ...

He and a colleague proved a theory advanced by the Nobel Prize winners James Watson and Francis Crick, who discovered DNA’s helical structure. By Delthia Ricks Franklin W. Stahl, a molecular biologist ...

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

In the constantly evolving field of forensic science, processing DNA quickly and accurately is paramount. Recent advances in technology have transformed the landscape of forensic DNA analysis, ...

Mitochondria — the powerhouses of cells — carry unique DNA that is mutated in specific diseases, causing cells to be starved of energy. Now, scientists have uncovered a first-of-its-kind molecule that ...