The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.
Native Read Sequencing for Methylation Profiling in Cancer and Neurodegenerative Disease Diagnostics
Methylation analysis holds significant promise for clinical diagnostics, yet its use has been limited due to challenges posed by legacy technologies that undermine clinical applicability, such as ...
Despite its utility, PCR’s main limitation is that it requires precise cycles of heating and cooling to amplify DNA. The thermal cyclers that perform this operation are clunky, relatively expensive, ...
In recent years, the study of epigenetics and its role in disease has increased dramatically. DNA methylation, which influences the ability of proteins to bind the DNA and thereby regulates gene ...
LONDON & LOS ANGELES--(BUSINESS WIRE)--DnaNudge, a medical and consumer genetics testing innovator and a spin-out of Imperial College London, today announced that it has signed a multi-million-dollar ...
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