Vision feels like a camera feed from the eyes, but new work on a hidden brain circuit suggests what we see is constantly edited by internal signals about how alert, focused, or distracted we are.

Investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects. Their work suggests a new target for treating anxiety ...

Deleting a gene called PTEN in certain brain cells disrupts the brain’s fear circuitry and triggers anxiety-like behavior in mice — key traits seen in autism. Researchers mapped how this genetic tweak ...

A single missing molecule in the brain is emerging as a powerful new clue to why learning and memory are altered in Down syndrome, and why those circuits might not be as fixed as once feared. By ...